The Impact of ALS-Associated Genes hnRNPA1, MATR3, VCP and UBQLN2 on the Severity of TDP-43 Aggregation

Amyotrophic lateral sclerosis is a progressive neurodegenerative disorder, characterized by cytoplasmic inclusions of RNA-binding protein TDP-43. Despite decades of research and identification of more than 50 genes associated with amyotrophic lateral sclerosis (ALS), the cause of TDP-43 translocatio...

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Detalles Bibliográficos
Autores principales: Bajc Česnik, Ana, Motaln, Helena, Rogelj, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465640/
https://www.ncbi.nlm.nih.gov/pubmed/32731393
http://dx.doi.org/10.3390/cells9081791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465640/
https://www.ncbi.nlm.nih.gov/pubmed/32731393
http://dx.doi.org/10.3390/cells9081791

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