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Iron Overload, Oxidative Stress and Calcium Mishandling in Cardiomyocytes: Role of the Mitochondrial Permeability Transition Pore

Iron (Fe) plays an essential role in many physiological processes. Hereditary hemochromatosis or frequent blood transfusions often cause iron overload (IO), which can lead to cardiomyopathy and arrhythmias; however, the underlying mechanism is not well defined. In the present study, we assess the hy...

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Detalles Bibliográficos
Autores principales: Gordan, Richard, Fefelova, Nadezhda, Gwathmey, Judith K., Xie, Lai-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465659/
https://www.ncbi.nlm.nih.gov/pubmed/32824344
http://dx.doi.org/10.3390/antiox9080758