Schwann Cell Autocrine and Paracrine Regulatory Mechanisms, Mediated by Allopregnanolone and BDNF, Modulate PKCε in Peripheral Sensory Neurons

Protein kinase type C-ε (PKCε) plays important roles in the sensitization of primary afferent nociceptors, such as ion channel phosphorylation, that in turn promotes mechanical hyperalgesia and pain chronification. In these neurons, PKCε is modulated through the local release of mediators by the sur...

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Detalles Bibliográficos
Autores principales: Bonalume, Veronica, Caffino, Lucia, Castelnovo, Luca F., Faroni, Alessandro, Giavarini, Flavio, Liu, Sheng, Caruso, Donatella, Schmelz, Martin, Fumagalli, Fabio, Carr, Richard W., Magnaghi, Valerio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465687/
https://www.ncbi.nlm.nih.gov/pubmed/32796542
http://dx.doi.org/10.3390/cells9081874

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465687/
https://www.ncbi.nlm.nih.gov/pubmed/32796542
http://dx.doi.org/10.3390/cells9081874

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