Cargando…

Schwann Cell Autocrine and Paracrine Regulatory Mechanisms, Mediated by Allopregnanolone and BDNF, Modulate PKCε in Peripheral Sensory Neurons

Protein kinase type C-ε (PKCε) plays important roles in the sensitization of primary afferent nociceptors, such as ion channel phosphorylation, that in turn promotes mechanical hyperalgesia and pain chronification. In these neurons, PKCε is modulated through the local release of mediators by the sur...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bonalume, Veronica, Caffino, Lucia, Castelnovo, Luca F., Faroni, Alessandro, Giavarini, Flavio, Liu, Sheng, Caruso, Donatella, Schmelz, Martin, Fumagalli, Fabio, Carr, Richard W., Magnaghi, Valerio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465687/ https://www.ncbi.nlm.nih.gov/pubmed/32796542 http://dx.doi.org/10.3390/cells9081874

Ejemplares similares

PKCε and allopregnanolone: functional cross-talk at the GABA(A) receptor level
por: Puia, Giulia, et al.
Publicado: (2015)

Stressing out the Hippo/YAP signaling pathway: toward a new role in Schwann cells
por: Melfi, S, et al.
Publicado: (2015)

Tumor suppressor Nf2/merlin drives Schwann cell changes following electromagnetic field exposure through Hippo-dependent mechanisms
por: Colciago, A, et al.
Publicado: (2015)

The Neurosteroid Allopregnanolone Modulates Specific Functions in Central and Peripheral Glial Cells
por: Faroni, Alessandro, et al.
Publicado: (2011)

Schwann cell development, maturation and regeneration: a focus on classic and emerging intracellular signaling pathways
por: Castelnovo, Luca Franco, et al.
Publicado: (2017)

Nerve Regenerative Effects of GABA-B Ligands in a Model of Neuropathic Pain
por: Magnaghi, Valerio, et al.
Publicado: (2014)

GPCRs in Autocrine and Paracrine Regulations
por: Tse, Lap Hang, et al.
Publicado: (2019)

Membrane progesterone receptors (mPRs/PAQRs) in Schwann cells represent a promising target for the promotion of neuroregeneration
por: Castelnovo, Luca F., et al.
Publicado: (2020)

Autocrine and paracrine mechanisms in reproductive endocrinology
Publicado: (1989)

GABA-B receptors in the PNS have a role in Schwann cells differentiation?
por: Procacci, Patrizia, et al.
Publicado: (2013)

Editorial on “New perspectives in neurosteroids action: a special player allopregnanolone”
por: Magnaghi, Valerio, et al.
Publicado: (2015)

PKCα integrates spatiotemporally distinct Ca(2+) and autocrine BDNF signaling to facilitate synaptic plasticity
por: Colgan, Lesley A, et al.
Publicado: (2018)

Autocrine and Paracrine Mechanisms Promoting Chemoresistance in Cholangiocarcinoma
por: Cadamuro, Massimiliano, et al.
Publicado: (2017)

Centella asiatica L. Phytosome Improves Cognitive Performance by Promoting Bdnf Expression in Rat Prefrontal Cortex
por: Sbrini, Giulia, et al.
Publicado: (2020)

M2 receptors activation modulates cell growth, migration and differentiation of rat Schwann-like adipose-derived stem cells
por: Piovesana, Roberta, et al.
Publicado: (2019)

Differentiation of adipose-derived stem cells into Schwann cell phenotype induces expression of P2X receptors that control cell death
por: Faroni, A, et al.
Publicado: (2013)

Adiponectin Action: A Combination of Endocrine and Autocrine/Paracrine Effects
por: Dadson, Keith, et al.
Publicado: (2011)

Network dynamics determine the autocrine and paracrine signaling functions of TNF
por: Caldwell, Andrew B., et al.
Publicado: (2014)

Regenerative Potential of DPSCs and Revascularization: Direct, Paracrine or Autocrine Effect?
por: Mattei, Vincenzo, et al.
Publicado: (2021)

Schwann cell proliferation in vitro is under negative autocrine control
Publicado: (1990)

The Autocrine/Paracrine Loop After Myocardial Stretch: Mineralocorticoid Receptor Activation
por: Ennis, Irene L, et al.
Publicado: (2013)

Growth Hormone and Reproduction: A Review of Endocrine and Autocrine/Paracrine Interactions
por: Hull, Kerry L., et al.
Publicado: (2014)

The adipokine leptin modulates adventitial pericyte functions by autocrine and paracrine signalling
por: Riu, Federica, et al.
Publicado: (2017)

VEGF is an autocrine/paracrine neuroprotective factor for injured retinal ganglion neurons
por: Froger, Nicolas, et al.
Publicado: (2020)

Autocrine/paracrine actions of growth hormone in human melanoma cell lines
por: Buckels, Ashiya, et al.
Publicado: (2019)

Paracrine and Autocrine Effects of VEGF Are Enhanced in Human eMSC Spheroids
por: Kozhukharova, Irina, et al.
Publicado: (2022)

Editorial: Small molecules and peptides in paracrine/autocrine regulation of ovarian folliculogenesis
por: Kim, So-Youn, et al.
Publicado: (2023)

Axonal tuning by GABA(A) receptor unveils novel tricks from an old dog
por: Bonalume, Veronica, et al.
Publicado: (2022)

Differential Roles of the PKC Novel Isoforms, PKCδ and PKCε, in Mouse and Human Platelets
por: Pears, Catherine J., et al.
Publicado: (2008)

Long-lasting BDNF signaling alterations in the amygdala of adolescent female rats exposed to the activity-based anorexia model
por: Mottarlini, Francesca, et al.
Publicado: (2022)

Autocrine/paracrine TGFβ1 is required for the development of epidermal Langerhans cells
por: Kaplan, Daniel H., et al.
Publicado: (2007)

XIAP gene expression and function is regulated by autocrine and paracrine TGF-β signaling
por: Van Themsche, Céline, et al.
Publicado: (2010)

The exosome-mediated autocrine and paracrine actions of plasma gelsolin in ovarian cancer chemoresistance
por: Asare-Werehene, Meshach, et al.
Publicado: (2019)

Mechanistic insights into autocrine and paracrine roles of endothelial GABA signaling in the embryonic forebrain
por: Choi, Yong Kee, et al.
Publicado: (2019)

Autocrine and Paracrine Effects of Vascular Endothelial Cells Promote Cutaneous Wound Healing
por: Lu, Yang, et al.
Publicado: (2021)

Using Chromatin-Nuclear Receptor Interactions to Quantitate Endocrine, Paracrine, and Autocrine Signaling
por: Taves, Matthew D., et al.
Publicado: (2020)

Repeated cocaine exposure during adolescence impairs recognition memory in early adulthood: A role for BDNF signaling in the perirhinal cortex
por: Mottarlini, Francesca, et al.
Publicado: (2020)

Kinetics of PKCε Activating and Inhibiting Llama Single Chain Antibodies and Their Effect on PKCε Translocation in HeLa Cells
por: Summanen, Milla, et al.
Publicado: (2012)

Gut Inflammation Induced by Finasteride Withdrawal: Therapeutic Effect of Allopregnanolone in Adult Male Rats
por: Diviccaro, Silvia, et al.
Publicado: (2022)

Cachectin/tumor necrosis factor exerts endocrine, paracrine, and autocrine control of inflammatory responses
Publicado: (1988)

Cannot write session to /tmp/vufind_sessions/sess_c0u2m9d4uovd4e96dqtpnqqtfr