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Cholesterol and Mevalonate: Two Metabolites Involved in Breast Cancer Progression and Drug Resistance through the ERRα Pathway

Breast cancer is the second greatest cause of cancer-related death in women. Resistance to endocrine treatments or chemotherapy is a limiting drawback. In this context, this work aims to evaluate the effects of cholesterol and mevalonate during tumor progression and their contribution in the onset o...

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Detalles Bibliográficos
Autores principales: Brindisi, Matteo, Fiorillo, Marco, Frattaruolo, Luca, Sotgia, Federica, Lisanti, Michael P., Cappello, Anna Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465765/
https://www.ncbi.nlm.nih.gov/pubmed/32751976
http://dx.doi.org/10.3390/cells9081819