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The role of the globular heads of the C1q receptor in TcdA-induced human colonic epithelial cell apoptosis via a mitochondria-dependent pathway

BACKGROUND: Clostridioides (formerly Clostridium) difficile infection is the leading cause of antibiotic-associated colitis. Studies have demonstrated that C. difficile toxin A (TcdA) can cause apoptosis of many human cell types. The purpose of this study was to investigate the relationships among e...

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Detalles Bibliográficos
Autores principales: Liang, Jinhua, Ning, Yongzhong, Dong, Li, Ma, Xiufeng, Li, Shu, Yang, Heran, Li, Qi, Chen, Ling, Gao, Lingjuan, Xu, Yanmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465811/
https://www.ncbi.nlm.nih.gov/pubmed/32878596
http://dx.doi.org/10.1186/s12866-020-01958-6