Systematic Analysis of Aberrant Biochemical Networks and Potential Drug Vulnerabilities Induced by Tumor Suppressor Loss in Malignant Pleural Mesothelioma

Background: Malignant pleural mesothelioma (MPM) is driven by the inactivation of tumor suppressor genes (TSGs). An unmet need in the field is the translation of the genomic landscape into effective TSG-specific therapies. Methods: We correlated genomes against transcriptomes of patients’ MPM tumors...

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Detalles Bibliográficos
Autores principales: Yang, Haitang, Xu, Duo, Yang, Zhang, Yao, Feng, Zhao, Heng, Schmid, Ralph A., Peng, Ren-Wang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465812/
https://www.ncbi.nlm.nih.gov/pubmed/32824422
http://dx.doi.org/10.3390/cancers12082310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465812/
https://www.ncbi.nlm.nih.gov/pubmed/32824422
http://dx.doi.org/10.3390/cancers12082310

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