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Reduced IκB-α Protein Levels in Peripheral Blood Cells of Patients with Multiple Sclerosis—A Possible Cause of Constitutive NF-κB Activation

NF-κB signaling pathways are dysregulated in both the central nervous system (CNS) and peripheral blood cells in multiple sclerosis (MS), but the cause of this is unknown. We have recently reported that peripheral blood mononuclear cells (PBMC) of patients with MS have increased constitutive activat...

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Detalles Bibliográficos
Autores principales: Yan, Jun, McCombe, Pamela A., Pender, Michael P., Greer, Judith M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465818/
https://www.ncbi.nlm.nih.gov/pubmed/32781504
http://dx.doi.org/10.3390/jcm9082534