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Gas6 Induces Myelination through Anti-Inflammatory IL-10 and TGF-β Upregulation in White Matter and Glia

The Gas6–TAM (Tyro3, Axl, Mer) ligand–receptor system is believed to promote central nervous system (CNS) (re)myelination and glial cell development. An additional important function of Gas6–TAM signalling appears to be the regulation of immunity and inflammation, which remains to be fully elucidate...

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Detalles Bibliográficos
Autores principales: Goudarzi, Salman, Gilchrist, Shannon E., Hafizi, Sassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465828/
https://www.ncbi.nlm.nih.gov/pubmed/32722558
http://dx.doi.org/10.3390/cells9081779