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Chemically Induced Hypoxia Enhances miRNA Functions in Breast Cancer

In aggressively growing tumors, hypoxia induces HIF-1α expression promoting angiogenesis. Previously, we have shown that overexpression of oncogenic microRNAs (miRNAs, miRs) miR526b/miR655 in poorly metastatic breast cancer cell lines promotes aggressive cancer phenotypes in vitro and in vivo. Addit...

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Detalles Bibliográficos
Autores principales: Gervin, Emma, Shin, Bonita, Opperman, Reid, Cullen, Mackenzie, Feser, Riley, Maiti, Sujit, Majumder, Mousumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465874/
https://www.ncbi.nlm.nih.gov/pubmed/32707933
http://dx.doi.org/10.3390/cancers12082008