Dual Inhibitory Action of a Novel AKR1C3 Inhibitor on Both Full-Length AR and the Variant AR-V7 in Enzalutamide Resistant Metastatic Castration Resistant Prostate Cancer

The expanded use of second-generation antiandrogens revolutionized the treatment landscape of progressed prostate cancer. However, resistances to these novel drugs are already the next obstacle to be solved. Various previous studies depicted an involvement of the enzyme AKR1C3 in the process of cast...

Descripción completa

Detalles Bibliográficos
Autores principales: Kafka, Mona, Mayr, Fabian, Temml, Veronika, Möller, Gabriele, Adamski, Jerzy, Höfer, Julia, Schwaiger, Stefan, Heidegger, Isabel, Matuszczak, Barbara, Schuster, Daniela, Klocker, Helmut, Bektic, Jasmin, Stuppner, Hermann, Eder, Iris E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465893/
https://www.ncbi.nlm.nih.gov/pubmed/32731472
http://dx.doi.org/10.3390/cancers12082092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465893/
https://www.ncbi.nlm.nih.gov/pubmed/32731472
http://dx.doi.org/10.3390/cancers12082092

Ejemplares similares