Ancient Evolutionary Origin of Intrinsically Disordered Cancer Risk Regions

Cancer is a heterogeneous genetic disease that alters the proper functioning of proteins involved in key regulatory processes such as cell cycle, DNA repair, survival, or apoptosis. Mutations often accumulate in hot-spots regions, highlighting critical functional modules within these proteins that n...

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Detalles Bibliográficos
Autores principales: Pajkos, Mátyás, Zeke, András, Dosztányi, Zsuzsanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465906/
https://www.ncbi.nlm.nih.gov/pubmed/32731489
http://dx.doi.org/10.3390/biom10081115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465906/
https://www.ncbi.nlm.nih.gov/pubmed/32731489
http://dx.doi.org/10.3390/biom10081115

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