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Design and Testing of a Custom Melanoma Next Generation Sequencing Panel for Analysis of Circulating Tumor DNA

Detection of melanoma-associated mutations using circulating tumor DNA (ctDNA) from plasma is a potential alternative to using genomic DNA from invasive tissue biopsies. In this study, we developed a custom melanoma next-generation sequencing (NGS) panel which includes 123 amplicons in 30 genes cove...

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Detalles Bibliográficos
Autores principales: Diefenbach, Russell J., Lee, Jenny H., Menzies, Alexander M., Carlino, Matteo S., Long, Georgina V., Saw, Robyn P. M., Howle, Julie R., Spillane, Andrew J., Scolyer, Richard A., Kefford, Richard F., Rizos, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465941/
https://www.ncbi.nlm.nih.gov/pubmed/32785074
http://dx.doi.org/10.3390/cancers12082228