Stromal CCL2 Signaling Promotes Mammary Tumor Fibrosis through Recruitment of Myeloid-Lineage Cells

Obesity is correlated with breast tumor desmoplasia, leading to diminished chemotherapy response and disease-free survival. Obesity causes chronic, macrophage-driven inflammation within breast tissue, initiated by chemokine ligand 2 (CCL2) signaling from adipose stromal cells. To understand how CCL2...

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Detalles Bibliográficos
Autores principales: Kuziel, Genevra, Thompson, Victoria, D’Amato, Joseph V., Arendt, Lisa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465971/
https://www.ncbi.nlm.nih.gov/pubmed/32731354
http://dx.doi.org/10.3390/cancers12082083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465971/
https://www.ncbi.nlm.nih.gov/pubmed/32731354
http://dx.doi.org/10.3390/cancers12082083

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