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Quantifying the Landscape and Transition Paths for Proliferation–Quiescence Fate Decisions

The cell cycle, essential for biological functions, experiences delicate spatiotemporal regulation. The transition between G1 and S phase, which is called the proliferation–quiescence decision, is critical to the cell cycle. However, the stability and underlying stochastic dynamical mechanisms of th...

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Detalles Bibliográficos
Autores principales: Chen, Zihao, Li, Chunhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466041/
https://www.ncbi.nlm.nih.gov/pubmed/32784979
http://dx.doi.org/10.3390/jcm9082582