TCGA mRNA Expression Analysis of the Heme Biosynthesis Pathway in Diffusely Infiltrating Gliomas: A Comparison of Typically 5-ALA Fluorescent and Non-Fluorescent Gliomas

5-Aminolevulinic acid (5-ALA) is a fluorescent dye that after metabolization to Protoporphyrin IX (PpIX) by the heme biosynthesis pathway typically leads to visible fluorescence in WHO grade IV but not grade II gliomas. The exact mechanism for high PpIX levels in WHO grade IV gliomas and low PpIX le...

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Detalles Bibliográficos
Autores principales: Mischkulnig, Mario, Kiesel, Barbara, Lötsch, Daniela, Roetzer, Thomas, Borkovec, Martin, Wadiura, Lisa I., Mercea, Petra A., Jaklin, Florian J., Hervey-Jumper, Shawn, Roessler, Karl, Berger, Mitchel S., Widhalm, Georg, Erhart, Friedrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466145/
https://www.ncbi.nlm.nih.gov/pubmed/32722247
http://dx.doi.org/10.3390/cancers12082043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466145/
https://www.ncbi.nlm.nih.gov/pubmed/32722247
http://dx.doi.org/10.3390/cancers12082043

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