Mathematical Modeling of MPNs Offers Understanding and Decision Support for Personalized Treatment

(1) Background: myeloproliferative neoplasms (MPNs) are slowly developing hematological cancers characterized by few driver mutations, with JAK2V617F being the most prevalent. (2) Methods: using mechanism-based mathematical modeling (MM) of hematopoietic stem cells, mutated hematopoietic stem cells,...

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Detalles Bibliográficos
Autores principales: Ottesen, Johnny T., Pedersen, Rasmus K., Dam, Marc J. B., Knudsen, Trine A., Skov, Vibe, Kjær, Lasse, Andersen, Morten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466162/
https://www.ncbi.nlm.nih.gov/pubmed/32751766
http://dx.doi.org/10.3390/cancers12082119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466162/
https://www.ncbi.nlm.nih.gov/pubmed/32751766
http://dx.doi.org/10.3390/cancers12082119

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