NCS 613, a Potent PDE4 Inhibitor, Displays Anti-Inflammatory and Anti-Proliferative Properties on A549 Lung Epithelial Cells and Human Lung Adenocarcinoma Explants

Chronic inflammation is a deleterious process occurring in several pulmonary diseases; it is a driving force promoting tumorigenesis. By regulating local cyclic nucleotide concentration, cyclic nucleotide phosphodiesterases (PDE) govern important biological processes, including inflammation and prol...

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Detalles Bibliográficos
Autores principales: Yougbare, Issaka, Belemnaba, Lazare, Morin, Caroline, Abusnina, Abdurazzag, Senouvo, Yannick F., Keravis, Thérèse, Lugnier, Claire, Rousseau, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466439/
https://www.ncbi.nlm.nih.gov/pubmed/32973507
http://dx.doi.org/10.3389/fphar.2020.01266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466439/
https://www.ncbi.nlm.nih.gov/pubmed/32973507
http://dx.doi.org/10.3389/fphar.2020.01266

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