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PEI-Mediated Transient Transfection of High Five Cells at Bioreactor Scale for HIV-1 VLP Production

High Five cells are an excellent host for the production of virus-like particles (VLPs) with the baculovirus expression vector system (BEVS). However, the concurrent production of high titers of baculovirus hinder the purification of these nanoparticles due to similarities in their physicochemical p...

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Detalles Bibliográficos
Autores principales: Puente-Massaguer, Eduard, Strobl, Florian, Grabherr, Reingard, Striedner, Gerald, Lecina, Martí, Gòdia, Francesc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466501/
https://www.ncbi.nlm.nih.gov/pubmed/32806511
http://dx.doi.org/10.3390/nano10081580