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Development of Novel Heparin/Protamine Nanoparticles Useful for Delivery of Exogenous Proteins In Vitro and In Vivo

We previously reported that heparin/protamine particles (LHPPs) produced as nanoparticles through simple mixing of raw materials exhibit sustained protein release and can be retained in cells. In the present study, we modified LHPPs without employing any organic synthetic approach. The resulting LHP...

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Detalles Bibliográficos
Autores principales: Nakamura, Shingo, Ando, Naoko, Ishihara, Masayuki, Sato, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466629/
https://www.ncbi.nlm.nih.gov/pubmed/32806578
http://dx.doi.org/10.3390/nano10081584