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Development of Novel Heparin/Protamine Nanoparticles Useful for Delivery of Exogenous Proteins In Vitro and In Vivo
We previously reported that heparin/protamine particles (LHPPs) produced as nanoparticles through simple mixing of raw materials exhibit sustained protein release and can be retained in cells. In the present study, we modified LHPPs without employing any organic synthetic approach. The resulting LHP...
Autores principales: | Nakamura, Shingo, Ando, Naoko, Ishihara, Masayuki, Sato, Masahiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466629/ https://www.ncbi.nlm.nih.gov/pubmed/32806578 http://dx.doi.org/10.3390/nano10081584 |
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