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Developmental Neurotoxicity Screening for Nanoparticles Using Neuron-Like Cells of Human Umbilical Cord Mesenchymal Stem Cells: Example with Magnetite Nanoparticles

Metallic nanoparticles (NPs), as iron oxide NPs, accumulate in organs, cross the blood-brain barrier and placenta, and have the potential to elicit developmental neurotoxicity (DNT). Human stem cell-derived in vitro models may provide more realistic platforms to study NPs effects on neural cells, an...

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Detalles Bibliográficos
Autores principales: Coccini, Teresa, Pignatti, Patrizia, Spinillo, Arsenio, De Simone, Uliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466682/
https://www.ncbi.nlm.nih.gov/pubmed/32824247
http://dx.doi.org/10.3390/nano10081607