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A Peptide-Based Nanocarrier for an Enhanced Delivery and Targeting of Flurbiprofen into the Brain for the Treatment of Alzheimer’s Disease: An In Vitro Study

Alzheimer’s disease (AD) is an age-related disease caused by abnormal accumulation of amyloid-β in the brain leading to progressive tissue degeneration. Flurbiprofen (FP), a drug used to mitigate the disease progression, has low efficacy due to its limited permeability across the blood–brain barrier...

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Detalles Bibliográficos
Autores principales: Al-azzawi, Shafq, Masheta, Dhafir, Guildford, Anna, Phillips, Gary, Santin, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466704/
https://www.ncbi.nlm.nih.gov/pubmed/32823499
http://dx.doi.org/10.3390/nano10081590