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Crystal structures of human ENPP1 in apo and bound forms

Cancer is one of the leading causes of mortality in humans, and recent work has focused on the area of immuno-oncology, in which the immune system is used to specifically target cancerous cells. Ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) is an emerging therapeutic target in human can...

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Detalles Bibliográficos
Autores principales: Dennis, Matthew L., Newman, Janet, Dolezal, Olan, Hattarki, Meghan, Surjadi, Regina N., Nuttall, Stewart D., Pham, Tam, Nebl, Tom, Camerino, Michelle, Khoo, Poh Sim, Monahan, Brendon J., Peat, Thomas S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466750/
https://www.ncbi.nlm.nih.gov/pubmed/32876064
http://dx.doi.org/10.1107/S2059798320010505