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Crystal structures of human ENPP1 in apo and bound forms
Cancer is one of the leading causes of mortality in humans, and recent work has focused on the area of immuno-oncology, in which the immune system is used to specifically target cancerous cells. Ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) is an emerging therapeutic target in human can...
Autores principales: | Dennis, Matthew L., Newman, Janet, Dolezal, Olan, Hattarki, Meghan, Surjadi, Regina N., Nuttall, Stewart D., Pham, Tam, Nebl, Tom, Camerino, Michelle, Khoo, Poh Sim, Monahan, Brendon J., Peat, Thomas S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466750/ https://www.ncbi.nlm.nih.gov/pubmed/32876064 http://dx.doi.org/10.1107/S2059798320010505 |
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