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SOD3 boosts T cell infiltration by normalizing the tumor endothelium and inducing laminin-α4

The conversion of a non-T cell-inflamed into a T cell-inflamed tumor microenvironment (TME) is a key to sensitizing tumors to T-cell-based immunotherapies. Recent data show that the extracellular superoxide dismutase (SOD3) alters endothelial basement membrane (EC-BM) composition, providing permissi...

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Detalles Bibliográficos
Autores principales: Carmona-Rodríguez, Lorena, Martínez-Rey, Diego, Mira, Emilia, Mañes, Santos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466848/
https://www.ncbi.nlm.nih.gov/pubmed/32934887
http://dx.doi.org/10.1080/2162402X.2020.1794163