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Trial watch: TLR3 agonists in cancer therapy

Toll-like receptor 3 (TLR3) is a pattern recognition receptor that senses exogenous (viral) as well as endogenous (mammalian) double-stranded RNA in endosomes. On activation, TLR3 initiates a signal transduction pathway that culminates with the secretion of pro-inflammatory cytokines including type...

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Detalles Bibliográficos
Autores principales: Le Naour, Julie, Galluzzi, Lorenzo, Zitvogel, Laurence, Kroemer, Guido, Vacchelli, Erika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466857/
https://www.ncbi.nlm.nih.gov/pubmed/32934877
http://dx.doi.org/10.1080/2162402X.2020.1771143