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Loss of Heterozygosity and Base Mutation Rates Vary Among Saccharomyces cerevisiae Hybrid Strains

A growing body of evidence suggests that mutation rates exhibit intra-species specific variation. We estimated genome-wide loss of heterozygosity (LOH), gross chromosomal changes, and single nucleotide mutation rates to determine intra-species specific differences in hybrid and homozygous strains of...

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Detalles Bibliográficos
Autores principales: Pankajam, Ajith V., Dash, Suman, Saifudeen, Asma, Dutta, Abhishek, Nishant, Koodali T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466981/
https://www.ncbi.nlm.nih.gov/pubmed/32727920
http://dx.doi.org/10.1534/g3.120.401551