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Gene Transcription as a Limiting Factor in Protein Production and Cell Growth

Cell growth is driven by the synthesis of proteins, genes, and other cellular components. Defining processes that limit biosynthesis rates is fundamental for understanding the determinants of cell physiology. Here, we analyze the consequences of engineering cells to express extremely high levels of...

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Detalles Bibliográficos
Autores principales: Metzl-Raz, Eyal, Kafri, Moshe, Yaakov, Gilad, Barkai, Naama
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466996/
https://www.ncbi.nlm.nih.gov/pubmed/32694199
http://dx.doi.org/10.1534/g3.120.401303