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Genome-Wide Dynamic Evaluation of the UV-Induced DNA Damage Response

Genetic screens in Saccharomyces cerevisiae have allowed for the identification of many genes as sensors or effectors of DNA damage, typically by comparing the fitness of genetic mutants in the presence or absence of DNA-damaging treatments. However, these static screens overlook the dynamic nature...

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Detalles Bibliográficos
Autores principales: Silva, Erica, Michaca, Manuel, Munson, Brenton, Bean, Gordon J., Jaeger, Philipp A., Licon, Katherine, Winzeler, Elizabeth A., Ideker, Trey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466999/
https://www.ncbi.nlm.nih.gov/pubmed/32732306
http://dx.doi.org/10.1534/g3.120.401417