Cargando…

Genome-Wide Dynamic Evaluation of the UV-Induced DNA Damage Response

Genetic screens in Saccharomyces cerevisiae have allowed for the identification of many genes as sensors or effectors of DNA damage, typically by comparing the fitness of genetic mutants in the presence or absence of DNA-damaging treatments. However, these static screens overlook the dynamic nature...

Descripción completa

Detalles Bibliográficos
Autores principales:	Silva, Erica, Michaca, Manuel, Munson, Brenton, Bean, Gordon J., Jaeger, Philipp A., Licon, Katherine, Winzeler, Elizabeth A., Ideker, Trey
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2020
Materias:	Mutant Screen Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466999/ https://www.ncbi.nlm.nih.gov/pubmed/32732306 http://dx.doi.org/10.1534/g3.120.401417

Ejemplares similares

Genetic Regulation of Dna2 Localization During the DNA Damage Response
por: Yimit, Askar, et al.
Publicado: (2015)

Leveraging DNA Damage Response Signaling to Identify Yeast Genes Controlling Genome Stability
por: Hendry, Jason A., et al.
Publicado: (2015)

Genome Profiling for Aflatoxin B(1) Resistance in Saccharomyces cerevisiae Reveals a Role for the CSM2/SHU Complex in Tolerance of Aflatoxin B(1)-Associated DNA Damage
por: St. John, Nick, et al.
Publicado: (2020)

Genome-Wide Screen for Haploinsufficient Cell Size Genes in the Opportunistic Yeast Candida albicans
por: Chaillot, Julien, et al.
Publicado: (2016)

A Genome-Wide Screen with Nicotinamide to Identify Sirtuin-Dependent Pathways in Saccharomyces cerevisiae
por: Choy, John S., et al.
Publicado: (2015)

Genome-Wide Screen for New Components of the Drosophila melanogaster Torso Receptor Tyrosine Kinase Pathway
por: Johns, Alex R., et al.
Publicado: (2018)

A Genome-Wide Screen for Genes Affecting Spontaneous Direct-Repeat Recombination in Saccharomyces cerevisiae
por: Novarina, Daniele, et al.
Publicado: (2020)

A Genome-Wide Screen for Sporulation-Defective Mutants in Schizosaccharomyces pombe
por: Ucisik-Akkaya, Esma, et al.
Publicado: (2014)

Genome-wide phenotypic RNAi screen in the Drosophila wing: global parameters
por: López-Varea, Ana, et al.
Publicado: (2021)

Genome-Wide Screen for Genes Involved in Caenorhabditis elegans Developmentally Timed Sleep
por: Huang, Huiyan, et al.
Publicado: (2017)

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes
por: López-Varea, Ana, et al.
Publicado: (2021)

A Genome-Wide Screen in Mice To Identify Cell-Extrinsic Regulators of Pulmonary Metastatic Colonisation
por: van der Weyden, Louise, et al.
Publicado: (2020)

Genome-wide screen identifies host loci that modulate Mycobacterium tuberculosis fitness in immunodivergent mice
por: Meade, Rachel K, et al.
Publicado: (2023)

Genome-Wide Screen for Context-Dependent Tumor Suppressors Identified Using in Vivo Models for Neoplasia in Drosophila
por: Groth, Casper, et al.
Publicado: (2020)

Genome-wide RNAi screen for regulators of UPR(mt) in Caenorhabditis elegans mutants with defects in mitochondrial fusion
por: Haeussler, Simon, et al.
Publicado: (2021)

A C. elegans genome-wide RNAi screen for altered levamisole sensitivity identifies genes required for muscle function
por: Chaya, Timothy, et al.
Publicado: (2021)

Identification of pathways modulating vemurafenib resistance in melanoma cells via a genome-wide CRISPR/Cas9 screen
por: Goh, Corinna Jie Hui, et al.
Publicado: (2021)

A Metagenome-Wide Association Study and Arrayed Mutant Library Confirm Acetobacter Lipopolysaccharide Genes Are Necessary for Association with Drosophila melanogaster
por: White, K. Makay, et al.
Publicado: (2018)

Identification of Saccharomyces cerevisiae Genes Whose Deletion Causes Synthetic Effects in Cells with Reduced Levels of the Nuclear Pif1 DNA Helicase
por: Stundon, Jennifer L., et al.
Publicado: (2015)

A Genome-Wide RNAi Screen for Enhancers of a Germline Tumor Phenotype Caused by Elevated GLP-1/Notch Signaling in Caenorhabditis elegans
por: Dalfó, Diana, et al.
Publicado: (2020)

Current genetic conservation of Chinese indigenous horses revealed with Y-chromosomal and mitochondrial DNA polymorphisms
por: Liu, Shuqin, et al.
Publicado: (2021)

Genomic Context Analysis of de Novo STXBP1 Mutations Identifies Evidence of Splice Site DNA-Motif Associated Hotspots
por: Uddin, Mohammed, et al.
Publicado: (2018)

RNAi-Based Suppressor Screens Reveal Genetic Interactions Between the CRL2(LRR-1) E3-Ligase and the DNA Replication Machinery in Caenorhabditis elegans
por: Ossareh-Nazari, Batool, et al.
Publicado: (2016)

A Screen of the Conserved Kinome for Negative Regulators of LIN-12 Negative Regulatory Region (“NRR”)-Missense Activity in Caenorhabditis elegans
por: Deng, Yuting, et al.
Publicado: (2019)

A Strategy To Isolate Modifiers of Caenorhabditis elegans Lethal Mutations: Investigating the Endoderm Specifying Ability of the Intestinal Differentiation GATA Factor ELT-2
por: Wiesenfahrt, Tobias, et al.
Publicado: (2018)

A Genetic Screen Reveals an Unexpected Role for Yorkie Signaling in JAK/STAT-Dependent Hematopoietic Malignancies in Drosophila melanogaster
por: Anderson, Abigail M., et al.
Publicado: (2017)

Detecting New Allies: Modifier Screen Identifies a Genetic Interaction Between Imaginal disc growth factor 3 and combover, a Rho-kinase Substrate, During Dorsal Appendage Tube Formation in Drosophila
por: Espinoza, Claudia Y., et al.
Publicado: (2020)

Genetic screen for suppressors of increased silencing in rpd3 mutants in Saccharomyces cerevisiae identifies a potential role for H3K4 methylation
por: Kleinschmidt, Richard A, et al.
Publicado: (2021)

A Chromatin-Focused siRNA Screen for Regulators of p53-Dependent Transcription
por: Sammons, Morgan A., et al.
Publicado: (2016)

Optimizing Genomic Methods for Mapping and Identification of Candidate Variants in ENU Mutagenesis Screens Using Inbred Mice
por: Geister, Krista A., et al.
Publicado: (2017)

Sleeping Beauty Transposon Mutagenesis as a Tool for Gene Discovery in the NOD Mouse Model of Type 1 Diabetes
por: Elso, Colleen M., et al.
Publicado: (2015)

Novel exc Genes Involved in Formation of the Tubular Excretory Canals of Caenorhabditis elegans
por: Al-Hashimi, Hikmat, et al.
Publicado: (2019)

A Method for Rapid Selection of Randomly Induced Mutations in a Gene of Interest Using CRISPR/Cas9 Mediated Activation of Gene Expression
por: Ng, William A., et al.
Publicado: (2020)

Drosophila Embryonic Cell-Cycle Mutants
por: Unhavaithaya, Yingdee, et al.
Publicado: (2013)

Comprehensive Synthetic Genetic Array Analysis of Alleles That Interact with Mutation of the Saccharomyces cerevisiae RecQ Helicases Hrq1 and Sgs1
por: Sanders, Elsbeth, et al.
Publicado: (2020)

A Forward Genetic Screen and Whole Genome Sequencing Identify Deflagellation Defective Mutants in Chlamydomonas, Including Assignment of ADF1 as a TRP Channel
por: Hilton, Laura K., et al.
Publicado: (2016)

Mutational Analysis of N-Ethyl-N-Nitrosourea (ENU) in the Fission Yeast Schizosaccharomyces pombe
por: Hoyos-Manchado, Rafael, et al.
Publicado: (2020)

A synthetic genetic array screen for interactions with the RNA helicase DED1 during cell stress in budding yeast
por: Carey, Sara B, et al.
Publicado: (2022)

RNAi Screen Identifies Novel Regulators of RNP Granules in the Caenorhabditis elegans Germ Line
por: Wood, Megan P., et al.
Publicado: (2016)

A Drosophila RNAi screen reveals conserved glioblastoma-related adhesion genes that regulate collective cell migration
por: Kotian, Nirupama, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_b0hu9gqaihm0ir1bbdo5329mbe