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Degradation of bacterial permeability family member A1 (BPIFA1) by house dust mite (HDM) cysteine protease Der p 1 abrogates immune modulator function

Bacterial permeability family member A1 (BPIFA1) is one of the most abundant proteins present in normal airway surface liquid (ASL). It is known to be diminished in asthmatic patients' sputum, which causes airway hyperresponsiveness (AHR). What is currently unclear is how environmental factors,...

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Detalles Bibliográficos
Autores principales: Zhang, Rui, Trower, Jessika, Wu, Tongde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7467078/
https://www.ncbi.nlm.nih.gov/pubmed/32890564
http://dx.doi.org/10.1016/j.ijbiomac.2020.08.214