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Cryo-EM as a powerful tool for drug discovery
The recent revolution in cryo-EM has produced an explosion of structures at near-atomic or better resolution. This has allowed cryo-EM structures to provide visualization of bound small-molecule ligands in the macromolecules, and these new structures have provided unprecedented insights into the mol...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier Ltd.
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7467112/ https://www.ncbi.nlm.nih.gov/pubmed/32890683 http://dx.doi.org/10.1016/j.bmcl.2020.127524 |