Discovery of HIV entry inhibitors via a hybrid CXCR4 and CCR5 receptor pharmacophore‐based virtual screening approach

Chemokine receptors are key regulators of cell migration in terms of immunity and inflammation. Among these, CCR5 and CXCR4 play pivotal roles in cancer metastasis and HIV-1 transmission and infection. They act as essential co-receptors for HIV and furnish a route to the cell entry. In particular, i...

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Detalles Bibliográficos
Autores principales: Mirza, Muhammad Usman, Saadabadi, Atefeh, Vanmeert, Michiel, Salo-Ahen, Outi M.H., Abdullah, Iskandar, Claes, Sandra, De Jonghe, Steven, Schols, Dominique, Ahmad, Sarfraz, Froeyen, Matheus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7467125/
https://www.ncbi.nlm.nih.gov/pubmed/32890663
http://dx.doi.org/10.1016/j.ejps.2020.105537

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7467125/
https://www.ncbi.nlm.nih.gov/pubmed/32890663
http://dx.doi.org/10.1016/j.ejps.2020.105537

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