Deep learning enables the atomic structure determination of the Fanconi Anemia core complex from cryoEM

Cryo-electron microscopy of protein complexes often leads to moderate resolution maps (4–8 Å), with visible secondary-structure elements but poorly resolved loops, making model building challenging. In the absence of high-resolution structures of homologues, only coarse-grained structural features a...

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Detalles Bibliográficos
Autores principales: Farrell, Daniel P., Anishchenko, Ivan, Shakeel, Shabih, Lauko, Anna, Passmore, Lori A., Baker, David, DiMaio, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2020
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7467173/
https://www.ncbi.nlm.nih.gov/pubmed/32939280
http://dx.doi.org/10.1107/S2052252520009306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7467173/
https://www.ncbi.nlm.nih.gov/pubmed/32939280
http://dx.doi.org/10.1107/S2052252520009306

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