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Patterns of Reliability: Assessing the Reproducibility and Integrity of DNA Methylation Measurement
DNA methylation plays an important role in both normal human development and risk of disease. The most utilized method of assessing DNA methylation uses BeadChips, generating an epigenome-wide “snapshot” of >450,000 observations (probe measurements) per assay. However, the reliability of each of...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7467214/ https://www.ncbi.nlm.nih.gov/pubmed/32885222 http://dx.doi.org/10.1016/j.patter.2020.100014 |