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Patterns of Reliability: Assessing the Reproducibility and Integrity of DNA Methylation Measurement

DNA methylation plays an important role in both normal human development and risk of disease. The most utilized method of assessing DNA methylation uses BeadChips, generating an epigenome-wide “snapshot” of >450,000 observations (probe measurements) per assay. However, the reliability of each of...

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Detalles Bibliográficos
Autores principales: Sugden, Karen, Hannon, Eilis J., Arseneault, Louise, Belsky, Daniel W., Corcoran, David L., Fisher, Helen L., Houts, Renate M., Kandaswamy, Radhika, Moffitt, Terrie E., Poulton, Richie, Prinz, Joseph A., Rasmussen, Line J.H., Williams, Benjamin S., Wong, Chloe C.Y., Mill, Jonathan, Caspi, Avshalom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7467214/
https://www.ncbi.nlm.nih.gov/pubmed/32885222
http://dx.doi.org/10.1016/j.patter.2020.100014