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Potentiating aminoglycoside antibiotics to reduce their toxic side effects

The lack of new antibiotics necessitates the improvement of existing ones, many of which are limited by toxic side effects. Aminoglycosides, antibiotics with excellent activity and low bacterial resistance, are hampered by dose-dependent toxic effects in patients (nephrotoxicity, ototoxicity). High...

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Detalles Bibliográficos
Autores principales: Rosenberg, Christopher R., Fang, Xin, Allison, Kyle R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7467299/
https://www.ncbi.nlm.nih.gov/pubmed/32877437
http://dx.doi.org/10.1371/journal.pone.0237948