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A comparison of humans and baboons suggests germline mutation rates do not track cell divisions

In humans, most germline mutations are inherited from the father. This observation has been widely interpreted as reflecting the replication errors that accrue during spermatogenesis. If so, the male bias in mutation should be substantially lower in a closely related species with similar rates of sp...

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Detalles Bibliográficos
Autores principales: Wu, Felix L., Strand, Alva I., Cox, Laura A., Ober, Carole, Wall, Jeffrey D., Moorjani, Priya, Przeworski, Molly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7467331/
https://www.ncbi.nlm.nih.gov/pubmed/32804933
http://dx.doi.org/10.1371/journal.pbio.3000838