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A comparison of humans and baboons suggests germline mutation rates do not track cell divisions
In humans, most germline mutations are inherited from the father. This observation has been widely interpreted as reflecting the replication errors that accrue during spermatogenesis. If so, the male bias in mutation should be substantially lower in a closely related species with similar rates of sp...
Autores principales: | Wu, Felix L., Strand, Alva I., Cox, Laura A., Ober, Carole, Wall, Jeffrey D., Moorjani, Priya, Przeworski, Molly |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7467331/ https://www.ncbi.nlm.nih.gov/pubmed/32804933 http://dx.doi.org/10.1371/journal.pbio.3000838 |
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