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Depletion of exosomal circLDLR in follicle fluid derepresses miR-1294 function and inhibits estradiol production via CYP19A1 in polycystic ovary syndrome

Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder in reproductive women and is characterized by polycystic ovaries, hyperandrogenism and chronic anovulation. Abnormal folliculogenesis is considered as a common characteristic of PCOS. Our aim is to identify the altered cir...

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Detalles Bibliográficos
Autores principales: Huang, Xin, Wu, Bi, Chen, Miaoxin, Hong, Ling, Kong, Pengcheng, Wei, Zhiyun, Teng, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7467373/
https://www.ncbi.nlm.nih.gov/pubmed/32651991
http://dx.doi.org/10.18632/aging.103602