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Glycochenodeoxycholic acid induces stemness and chemoresistance via the STAT3 signaling pathway in hepatocellular carcinoma cells

The poor prognosis of hepatocellular carcinoma (HCC) is primarily attributed to its high frequency of recurrence and resistance to chemotherapy. Epithelial-to-mesenchymal transition (EMT) and the acquisition of cancer stem cells (CSCs) are the fundamental drivers of chemoresistance in HCC. Glycochen...

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Detalles Bibliográficos
Autores principales: Shi, Changying, Yang, Jiamei, Hu, Longmiao, Liao, Boyi, Qiao, Liang, Shen, Weifeng, Xie, Feng, Zhu, Guoqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7467378/
https://www.ncbi.nlm.nih.gov/pubmed/32756004
http://dx.doi.org/10.18632/aging.103751