Raman Spectroscopy to Monitor Post-Translational Modifications and Degradation in Monoclonal Antibody Therapeutics

[Image: see text] Monoclonal antibodies (mAbs) represent a rapidly expanding market for biotherapeutics. Structural changes in the mAb can lead to unwanted immunogenicity, reduced efficacy, and loss of material during production. The pharmaceutical sector requires new protein characterization tools...

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Detalles Bibliográficos
Autores principales: McAvan, Bethan S., Bowsher, Leo A., Powell, Thomas, O’Hara, John F., Spitali, Mariangela, Goodacre, Royston, Doig, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7467412/
https://www.ncbi.nlm.nih.gov/pubmed/32614170
http://dx.doi.org/10.1021/acs.analchem.0c00627

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7467412/
https://www.ncbi.nlm.nih.gov/pubmed/32614170
http://dx.doi.org/10.1021/acs.analchem.0c00627

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