Pharmacokinetics and Dialyzability of a Single Oral Dose of Amenamevir, an Anti-Herpes Drug, in Hemodialysis Patients

INTRODUCTION: Amenamevir (ASP2151), a herpesvirus helicase-primase inhibitor, is currently used for the treatment of herpes zoster in Japan. Amenamevir is mainly metabolized in the liver, and urinary excretion of amenamevir is approximately 10% in healthy adults. The increase of systemic exposure in...

Descripción completa

Detalles Bibliográficos
Autores principales: Tsuruoka, Shuichi, Endo, Takamasa, Seo, Mizuna, Hashimoto, Naoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7467425/
https://www.ncbi.nlm.nih.gov/pubmed/32440976
http://dx.doi.org/10.1007/s12325-020-01375-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7467425/
https://www.ncbi.nlm.nih.gov/pubmed/32440976
http://dx.doi.org/10.1007/s12325-020-01375-1

Ejemplares similares