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Harnessing Conformational Plasticity to Generate Designer Enzymes

[Image: see text] Recent years have witnessed an explosion of interest in understanding the role of conformational dynamics both in the evolution of new enzymatic activities from existing enzymes and in facilitating the emergence of enzymatic activity de novo on scaffolds that were previously non-ca...

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Detalles Bibliográficos
Autores principales: Crean, Rory M., Gardner, Jasmine M., Kamerlin, Shina C. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7467679/
https://www.ncbi.nlm.nih.gov/pubmed/32496764
http://dx.doi.org/10.1021/jacs.0c04924