Antagonistic control of Caenorhabditis elegans germline stem cell proliferation and differentiation by PUF proteins FBF-1 and FBF-2

Stem cells support tissue maintenance, but the mechanisms that coordinate the rate of stem cell self-renewal with differentiation at a population level remain uncharacterized. We find that two PUF family RNA-binding proteins FBF-1 and FBF-2 have opposite effects on Caenorhabditis elegans germline st...

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Detalles Bibliográficos
Autores principales: Wang, Xiaobo, Ellenbecker, Mary, Hickey, Benjamin, Day, Nicholas J, Osterli, Emily, Terzo, Mikaya, Voronina, Ekaterina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7467723/
https://www.ncbi.nlm.nih.gov/pubmed/32804074
http://dx.doi.org/10.7554/eLife.52788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7467723/
https://www.ncbi.nlm.nih.gov/pubmed/32804074
http://dx.doi.org/10.7554/eLife.52788

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