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Antagonistic control of Caenorhabditis elegans germline stem cell proliferation and differentiation by PUF proteins FBF-1 and FBF-2
Stem cells support tissue maintenance, but the mechanisms that coordinate the rate of stem cell self-renewal with differentiation at a population level remain uncharacterized. We find that two PUF family RNA-binding proteins FBF-1 and FBF-2 have opposite effects on Caenorhabditis elegans germline st...
Autores principales: | Wang, Xiaobo, Ellenbecker, Mary, Hickey, Benjamin, Day, Nicholas J, Osterli, Emily, Terzo, Mikaya, Voronina, Ekaterina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7467723/ https://www.ncbi.nlm.nih.gov/pubmed/32804074 http://dx.doi.org/10.7554/eLife.52788 |
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