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Mechanisms underlying genome instability mediated by formation of foldback inversions in Saccharomyces cerevisiae
Foldback inversions, also called inverted duplications, have been observed in human genetic diseases and cancers. Here, we used a Saccharomyces cerevisiae genetic system that generates gross chromosomal rearrangements (GCRs) mediated by foldback inversions combined with whole-genome sequencing to st...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7467729/ https://www.ncbi.nlm.nih.gov/pubmed/32762846 http://dx.doi.org/10.7554/eLife.58223 |