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Stem cell niche exit in C. elegans via orientation and segregation of daughter cells by a cryptic cell outside the niche
Stem cells reside in and rely upon their niche to maintain stemness but must balance self-renewal with the production of daughters that leave the niche to differentiate. We discovered a mechanism of stem cell niche exit in the canonical C. elegans distal tip cell (DTC) germ stem cell niche mediated...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7467730/ https://www.ncbi.nlm.nih.gov/pubmed/32692313 http://dx.doi.org/10.7554/eLife.56383 |