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Stem cell niche exit in C. elegans via orientation and segregation of daughter cells by a cryptic cell outside the niche

Stem cells reside in and rely upon their niche to maintain stemness but must balance self-renewal with the production of daughters that leave the niche to differentiate. We discovered a mechanism of stem cell niche exit in the canonical C. elegans distal tip cell (DTC) germ stem cell niche mediated...

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Detalles Bibliográficos
Autores principales: Gordon, Kacy L, Zussman, Jay W, Li, Xin, Miller, Camille, Sherwood, David R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7467730/
https://www.ncbi.nlm.nih.gov/pubmed/32692313
http://dx.doi.org/10.7554/eLife.56383