Cargando…

The First Total Synthesis of the Lipid Mediator PD2(n-3 DPA)

[Image: see text] The resolution of inflammation is governed by the active biosynthesis of specialized pro-resolving mediators using ω-6 and ω-3 polyunsaturated fatty acids as substrates. These mediators act as resolution agonists and display several interesting bioactivities. PD2(n-3 DPA) is an oxy...

Descripción completa

Detalles Bibliográficos
Autores principales: Tungen, Jørn Eivind, Primdahl, Karoline Gangestad, Hansen, Trond Vidar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society and American Society of Pharmacognosy 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7467816/
https://www.ncbi.nlm.nih.gov/pubmed/32543839
http://dx.doi.org/10.1021/acs.jnatprod.0c00385