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Aberrant DNA methylation results in altered gene expression in non-alcoholic steatohepatitis-related hepatocellular carcinomas

PURPOSE: The aim of this study was to investigate DNA methylation alterations in non-alcoholic steatohepatitis (NASH)-related hepatocellular carcinomas (HCCs). METHODS: Genome-wide DNA methylation analysis was performed using the Infinium Human Methylation 450 K BeadChip, and levels of mRNA expressi...

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Detalles Bibliográficos
Autores principales: Tian, Ying, Arai, Eri, Makiuchi, Satomi, Tsuda, Noboru, Kuramoto, Junko, Ohara, Kentaro, Takahashi, Yoriko, Ito, Nanako, Ojima, Hidenori, Hiraoka, Nobuyoshi, Gotoh, Masahiro, Yoshida, Teruhiko, Kanai, Yae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7467955/
https://www.ncbi.nlm.nih.gov/pubmed/32685988
http://dx.doi.org/10.1007/s00432-020-03298-4